Meдицина/8. Mорфология
assistant
Skoruk A.G.
Department
of pathology, forensic medicine and law
Vinnitsa
national Pirogov memorial medical university Vinnitsa, Ukraine
The topographicanatomical
features neurovascular bundles of the upper mediastinum in five months human
fetuses
The study of formation and topography of organs and
structures of the fetus has particular importance for the interpretation of the
true flow processes of organogenesis. Especially it is useful today, during the
rapidly development of modern endoscopic surgery that requires extensive
research morphologists regularities of the structure and formation topographicanatomical
relationships of organs and structures of various systems in the fetal period
of human ontogenesis. The adequate sonographic conducting research, operations
on the organs of the fetus in the womb, the interpretation of the results of
modern diagnostic techniques (CT, MRI) and autopsy of the fetus are based on
objective anatomical data [1, 4, 6, 7]. Recently, much attention is paid to
individual variability structures of the human body. One of the most variable
systems is vascular. In the scientific literature highlights the disparate
evidences about peculiarities of formation and morphogenesis topography
components neurovascular bundles [2, 3, 5, 8]. However, information about
typical and variant anatomy of the great vessels of the upper mediastinum and
the establishment of the correlation of relationships during the fetal period
of prenatal human ontogenesis remain poorly understood and require further
investigation.
The aim of the work was to determine syntopy main neurovascular bundles of the
upper mediastinum in five-month human fetuses.
Materials and methods. The researches of 6-man
fetuses preparations 136,0-185,0 mm parietal-coccygeal length are carried out
by methods of preparing thin thymus and mediastinal organs controlled binocular
loupe, morphometry, macro- and microscopy-based in Vinnitsa pathoanatomical
bureau. The study was conducted in compliance with the guidelines of bioethics
and in accordance with the order of the Ministry of Health of Ukraine № 690
from 23.09.2009
Discussion of results. The investigations of
variant anatomy of the aortic arch branches and changes in syntopy components
left and right neurovascular bundles neck are topical urgent and priority. The
group of fetuses of the 5th month of fetal development include fetuses
136,0-185,0 mm parietal-coccygeal length. At the end of the 5th month of fetal
development (fetus 185.0 mm parietal-coccygeal length) of a convex semicircle aortic
arch with length 12.2 mm, four arteries originate: shoulder-main trunk, left
common carotid artery, left vertebral artery and the left subclavian artery. In
front to the convexity of the aortic arch and the initial parts of the above
vessels that depart from her left shoulder, adjoins the main vein.
Shoulder-head stem, length 7.3 mm, directed upwards and slightly to the right,
and its rear surface adjacent to anterolateral surface of the trachea. At 5.5
mm above the right sterno-clavicular joint shoulder-main trunk divides into the
right common carotid artery and right subclavian artery. The side of the right
common carotid artery runs right internal jugular vein, and behind in the
groove between them - right vagus nerve. At 4.2 mm above the upper edge of the
thyroid cartilage of the right common carotid artery divides into the external
and internal carotid arteries. The left common carotid artery passes in front
of the transverse processes of the cervical vertebrae. Medialy to the left
common carotid artery are placed the esophagus and trachea. At the level of the
upper edge of the thyroid cartilage left common carotid artery divides into the
external and internal carotid arteries. The feature branches from the aortic
arch of the fetus is a discharge between the left common carotid artery and
left subclavian artery, left vertebral artery. The neck portion of the right
vertebral artery tight to the lateral surface of the left common carotid
artery. The left vertebral artery enters the transverse hole III-th cervical
vertebra, climbs up on the same hole two upper cervical vertebrae and enters
the cranial cavity through the large hole occipital bone. The left vagus nerve
within the upper mediastinum tight adjacent to anterolateral surface of the
left vertebral artery. Intrathoracic portion of the left subclavian artery
located at 4.0 mm below from the left brachiocephalic vein.
Conclusions. 1. Most of the five-month topical fetuses position adjacent to the
mediastinal structures thymus (ascending aorta, aortic arch and its branches,
superior vena cava, the vagus nerve and diaphragm) depends on the formation of
the topography of the mediastinum. 2. In a minority of cases (1 of 6) present
individual anatomical features of vessels, which may be the cause of some
difficulties for the sonographic diagnosis and during endoscopic surgery in the
fetus and newborn.
Literature:
1. Исследование
закономерностей морфометрических параметров органов и структур в перинатальном
периоде онтогенеза / Ю.Т. Ахтемийчук, А.Н. Слободян, Д.В. Проняев, И. А. Семянив //
Морфология. – 2010. – Т. 137, № 4. – С. 22.
2. Корелятивні взаємовідношення стравоходу і аорти в
пренатальному онтогенезі людини / О. Ф. Марчук, Ю. Ф. Марчук, Т. В. Хмара [та
ін.] // Хист. – 2008. – Вип. 10. – С. 111.
3. Марчук Ф. Д. Топографія блукаючих нервів у передплодів людини / Ф. Д. Марчук, Т. В. Хмара, Р. П. Гулик //
Морфологічний стан тканин і органів систем
організму в нормі та патології. – Тернопіль: Укрмедкнига, 2009. – С. 208.
4. Нариси перинатальної анатомії / Ю. Т. Ахтемійчук, О. М. Слободян, Т. В. Хмара [та ін.]; за ред. Ю. Т. Ахтемійчука.
– Чернівці: БДМУ, 2011. – С. 9-14.
5.
Топографія і морфологічна
характеристика непарної та напівнепарної вен у передплодів людини / А. С.
Головацький, Т. Ф. Росола, О. І. Гецко [та ін.] // Наук. вісник Ужгород.
унів-ту, серія „Медицина”. – 2009. – Вип. 35. – С. 24-27.
6. Di Naro E. Fetal thymic involution: a sonographic marker of the inflammatory syndrome / E. Di Naro, A. Cromi, F. Ghezzi // Am. J.
Obstet. and Gyn. – 2006. – Vol. 194, № 1. – P. 153-159.
7. Ioannides A. S. Role of Sonic hedgehod in the
development of the trachea and oesophagus / A. S. Ioannides, D. J. Henderson,
E. Spitz [et al.] // J. Pediatr. Surg. – 2003. – Vol. 38. – P. 3627-3629.
8. Ozdemir B. Multiple variations in the azygos
venous system: a preaortic interazygos vein and the absence of hemiazygos vein
/ B. Ozdemir, M. M. Aldur, H. H. Celik // Surg. Radiol. Anat. – 2002. – Vol.
24. – P. 68-70.