Korazbekova K.U. 1,2, Utemisova G.S.1, Zhylysbayeva A.N.1,2

1Regional social and innovative university, Shymkent, Kazakhstan

2M.Auezov South Kazakhstan State University, Shymkent, Kazakhstan

 

Study of antibacterial properties of propolis from South Kazakhstan region

 

Propolis is beekeeping additional minor product. Propolis is used for therapeutic purposes by people and bees since ancient times. Propolis, especially in ancient Egypt was a very well-known [1-3]. Propolis is a resin material with green, brown or green-brown color, and it has positive smell of poplar bud and smell of honey, vanilla, and honeycombs. Bees collect propolis from bud of a number of trees and grasses and it is used for slot disinfection. It contains 55% of the resin, 30% of the wax substances, 10% of the essential oil and 5% of the pollen rich in vitamins and microelements. Propolis is not yet fully defined substance, that’s why it has not chemical formula. On the basis of scientific research and practice known to many years, doctors, bacteriologists, biologists defined a lot of self-healing qualities of propolis as a natural product [1-2; 4-5]. In this paper is given research results of bactericidal properties of propolis taken from South Kazakhstan region.

Research of bactericidal properties of propolis was carried out at the "Bacteriological Laboratory" of the Clinic of the International Kazakh-Turkish University. Four types of bacteria such as staphylococcus, diphtheria and dysentery bacillus and Salmonella typhimurium were used in our experiments. Antibacterial properties of propolis were studied in 1:1, 1:5, and 1:10 ratio solutions. All cultured bacteria in Petri dishes were incubated in thermostat and they were observed every 30 minutes, 3 hours, and 24 hours to track changes.

The results of the experiment of the bactericidal properties of propolis are shown in Table 1.

Propolis solution in the ratio 1: 1 does not show bacterial growth after 30 minutes, 3 hours, and 24 hours of observation in all Petri dishes. Propolis solution in 1:5 ratio during time points of 30 minutes, 3 hours, and 24 hours showed positive impact on staphylococcus and diphtheria, but bacterial growth was revealed in all Petri dishes with cultivation of dysentery bacillus and Salmonella typhimurium. Observation of antibacterial property of the propolis solution in 1:5 ratios shows positive impact only for diphtheria after 30 minutes, 3 hours, and 24 hours, but other three bacteria - staphylococcus, dysentery bacillus and Salmonella continue grow during one day study.

Table 1. Results of the study of antibacterial properties of propolis

 

 

Name of the bacteria

after 30 minutes

after 3 hours

after 24 hours

Control culture

 

1:1

 

1:5

 

1:10

Control culture

 

1:1

 

1:5

 

1:10

Control culture

 

1:1

 

1:5

 

1:10

1. Staphylococcus

 

+

 

-

 

-

 

+

 

+

 

-

 

-

 

+

 

+

 

-

 

-

 

+

2. Diphtheria

 

+

 

-

 

-

 

-

 

+

 

-

 

-

 

-

 

+

 

-

 

-

 

-

3. Dysentery

 

+

 

-

 

+

 

+

 

+

 

-

 

+

 

+

 

+

 

-

 

+

 

+

4. Salmonella typhi murium

 

+

 

-

 

+

 

+

 

+

 

-

 

+

 

+

 

+

 

-

 

+

 

+

“+” – growth is observed                                              “-” – growth is not observed                                             

 

After 24-day observation Petri dishes with cultivated dysentery and Salmonella in 1:5 and 1:10 ratios solution of propolis were put to the thermostat for further study. These two bacteria in propolis solution of 1:5 and 1:10 ratio stop their growth only after eight days.

In general, propolis solutions in 1:1 ratio has a powerful effect on staphylococcus, diphtheria, dysentery, and Salmonella typhimurium within 30 minutes in the experiments carried out to determine the antibacterial properties of propolis. Propolis solution in 1:5 ratio did not affect only Salmonella typhimurium and dysentery, ie, growth was not stopped. And propolis solution in 1:10 ratio has affected only to diphtheria. But after 8 days of observation all three spices of bacteria died in the propolis solution of 1:5 and 1:10 ratio. The results of experiments show that propolis is a natural product with a high-quality bactericidal properties.

 

References

1.     Пономарева Е.Г. Кормовая база пчеловодства и опыление сельскохозяйственных растений. – М.: Колос, 1980 г . – 255 с.

2.     Пономарева Е.Т., Детерлеева Н.Б. Медоносные рессурсы и опыление сельскохозяйственных растений.-М.: Агропромиздат, 1986 г. – 224 с.

3.     Прополис: ценный продукт пчеловодства. – Бухарест: Апимондия, 1987 г.

4.     Под ред. Виноградов Т.В., Зайцев Г.П. Пчела и здоровье человека. –М.: Россельхозиздат, 1964г. – 300 с.

5.     Апимондия. Апитерапия сегодня. Бухарест, 1988г. – 150 с.