Biological sciences/11. Bioengineering and Bioinformatics

 

L.V.Skripnikova Technical Science Candidate, Associate Professor

State University after Shakarim Semey City, Republic of Kazakhstan

 

On regulation of genetically engineered activity

in the Republic of Kazakhstan

The article contains information on a rating of the dangerous products containing the genetically modified organisms (GMO), consequences of their usage for the health of a person, creation of legal base in the field of usage of results of genetically engineered activity and work of  Kazakhstani specialized laboratories on examination of goods on the maintenance of GMO.

Keywords: genetically modified organisms (GMO), transgene products, danger, safety, threat, risk, chemical pollution, genes, mutation, cancer genic effect, immunity, allergic reactions, antibiotics, ecology, health, and environment.

The main direction of world researches in the field of genetic engineering is concentrated on GMO creation with these or those signs useful to the person, not having analogs in the nature. But it must be kept in mind that genetic engineering, on the one hand, is the powerful tool of progress, and on the other hand, at careless use, can have negative consequences. In the different countries of the world of the relation to this problem aren't unambiguous [1].

Now in many countries there is a percentage ban on use of such products, for example: in Japan standard of the maintenance of GMO in a product – 5%; in Europe – it is no more than 0,9%; and in the USA – 10%. Almost worldwide a product marking about the maintenance of GMO in it is obligatory [2].

Scientists of CIS countries - Russia, Ukraine, Kazakhstan with its Institute of Eco hygiene and Toxicology, National Medical Academy, Scientific Research Institute of Food and Medical centers have been working over creation of a rating of the dangerous products containing GMO. As a result, the most dangerous 10 products were called and about this result was told on the first Kaliningrad Symposium "Food. Health. Life". Harm of the products got to the list, was defined according to their ability to cause a serious illness. Many "participants" of a rating often become the reasons of poisonings and heavy allergic reactions, but for healthy people these products are quite safe. According to doctors, everything depends on a dosage. Intake of such food in small amounts can be quite harmless [3].

The 1st place: chips and sparkling water. Chips are a mix of carbohydrates and fat, in a cover of dyes and taste substitutes. In chips carcinogens - the substances provoking a cancer are formed. And the hydrogenated fats lead to rising of the level of cholesterol in blood that increases risk of heart attacks and strokes. The sweet sparkling drinks - mix of sugar, chemistry and gases, contain aspartame (E951), a synthetic sugar substitute. Felatanin containing in aspartame changes a sensitivity threshold, usage of it in big doses promotes development of a maniacal depression, attacks of a panic, rage and violence. Sparkling water with the aspartame doesn't satisfy thirst. After the usage of drinks in a mouth there is a feeling of excessive sweetness which one wants to be removed with a new portion of drink. As a result, drinks with aspartame become drinks for thirst excitement, instead of its satisfying. Besides, benzoate of sodium (E211) which is used as a preservative oppresses enzymes that lead to a metabolic disorder and obesity.

The 2nd place: fast food. The fastest food - belyashes, chebureks, French fries, doner kebabs, in general everything that is fried - are very harmful. Such food leads to violation in the field of digestion - to colitis, gastritis, heartburn, etc. Other kinds of fast food are chips, croutons, nuts, chocolate and nut bars and others.  Nutritionists of the whole world are sure that food determines duration and quality of human life. And flavoring habits remain with the person for the rest of life. How to be disaccustomed to the fast food usage? There is only one way out - to exclude fast-food completely from a diet.

The 3rd place: sausage, smoked products. All kinds of smoked sausages – a product which we most often buy, contains more and more fragrances and dyes, than meat. Smoked meat and fish got to a rating list too for the high content of carcinogens. They are formed in processing in the form of substance of petrolpyrene. More and more producers pass to the gene modified raw materials. For example, for 80% many kinds of sausages consist of transgene soy. Only one slice of smoked sausage contains so many phenolic connections that how many the person inhales in the city in a year. Phenol is extremely toxic.

The 4th place: vegetables, fruit, products with preservatives. Even the most useful and natural products can become harmful if they are grown up, for example, near the highway or a plant. Using such vegetables, it is possible to receive a high share of petrolpyrene and other substances causing a cancer. Preservatives may contain glutamate sodium poisoning of which appears in the form of a headache, angiospasms and even a metabolic disorder.

5 place: margarine, cakes, and cereals. Margarine is a transgene fat - the most harmful type of fat. Products with its contents - cakes, pies with cream, products from flaky pastry - are harmful. The use of these sated with sugar and fat of products practically guarantees a metabolic disorder and excess of weight. Cereals, in particular, a white loaf, got to the list because it often causes intolerance. The illness is called as Gee’s disease. Symptoms fluctuate from problems with intestines to diabetes and infertility.

The 6th place: coffee, energy drinks, milk. During a day an adult can drink two-three cups without risking exhausting the nervous system. It is better to take energy drinks as seldom as possible. Milk, as well as bread, also is an intolerable product. Poisoning with milk proteins in hard cases can lead even to a lethal outcome.

The 7th place: home vegetable conservation, ice cream. These products can be eaten bravely if to make home conservations due to the strict rules and norms of dosage that is to observe a dosage of products and not to neglect elementary food safety (the correct sterilization). An ice cream contains thickeners and fragrances which can slow down a metabolism, and it is the increased risk of emergence of weight excess.

The 8th place: chewing candies, fruit candies, Chupa chups. These products contain a huge amount of sugar, chemical additives, dyes, substitutes, etc.

The 9th place: chocolate bars. They contain a large number of calories in combination with the chemical additives which have been genetically modified by products, dyes and fragrances.

The 10th place: mayonnaise. Mayonnaise contains a trance fats which are cancer genic and cause an increase of level of cholesterol. It is impossible to use mayonnaise in plastic packages - vinegar allocates cancer genic substances from plastic. Mayonnaise contains a large amount of preservatives and stabilizers. A number of harmful products is also a wide range of ketchups, various sauces and soup appetizers which contain dyes, substitutes of taste [4, 5, 6].

We will generalize the main risks of the usage of products with GMO:

• Immunity easing, possibility of allergic reactions as a result of direct effect of transgene proteins;

• Emergence of stability of a person to antibiotics that will make impossible process of treatment of many diseases;

• The violations of health connected with accumulation in a human body of herbicides as GM-plants have property to accumulate them [7].

In this regard Kazakhstan needs to have a reliable protection on a fundamental and scientific basis, by means of the organization of highly skilled control services of use of products of biotechnology. Now in the republic the technical regulations exist in which it is specified work that products of GMO have to be marked. Kazakhstani specialized laboratories at the Republican Academy of Food, in such cities as Astana, Alma-Ata, Ust-Kamenogorsk, Petropavlovsk and Uralsk already began a work on examination of goods on the maintenance of GMO. If the percentage of the contents in a studied product equals 0,9%, it considers harmless and will not be marked.

At the same time lack of universal control of GMO circulation in Kazakhstan is a legal way allowing producers of food products, freely to import the biological products containing GMO.

However it should be noted that in some separate KZ laws there are the norms governing the public relations in the field of use of results of genetically engineered activity anyway. They are the following:

• The Code of RK "About Health of the People and Health System", September 18, 2009;

•The Ecological Code of the RK, January 9, 2007;

• The Law of the RK "About Ratification of the Kartakhensky Protocol on Biosafety to the Convention on Biological Diversity", June 17, 2008;

• The Law of the RK "About Safety of Food Products", July 21, 2007;

• The Law of the RK "About Seed Farming", on February 8, 2008.

Absence of the separate law regulating genetically engineered activity in Kazakhstan led to impossibility of formation of a legal framework for legitimate implementation of genetically engineered activity. In this regard adoption of the Law "About State Regulation of Genetically Engineered Activity", including a turn and development of GMO is planned. But for implementation of provisions of the specified laws Resolutions of the government of the RK "About the Approval of Rules of a Turn" and "About the Approval of Rules of Work on Scientific on Reasonable Grounds Confirmation of Safety of Genetically Modified Objects" are adopted.

Recently questions of biosafety came to the forefront in system of the international relations. In 2000 Convention member countries "About biological diversity" adopted the Kartakhensky protocol on the biosafety, which main objective is an assistance in providing an appropriate level of protection when using the live changed organisms. 163 countries are members of this Protocol, including EU countries, China, India, and Japan. Kazakhstan ratified the Kartakhensky protocol on June 17, 2008 in this connection assumed obligations for development and adoption of the relevant legislation, creation of administrative bodies or investment with appropriate authority already existing bodies [8,9].

Development of genetic engineering and its achievement will promote development of economy of our country, by creation of the new products surpassing in quality traditional analogs. However, developing genetic engineering it is necessary to remember the potential risks arising at use of GMO. Therefore it is necessary to be guided by legislative and legal and normative and technical base for development of genetic engineering as fundamental science, to exercise control of GMO use for the purpose of safety and population health.

 

Literature:

1 Skripnikova L.V. Danger of the genetically modified organisms (GMO) for health of a person and the earth ecology. Scientific magazine "Semey State Shakarim University Bulletin", No. 2 (62), I volume, 2013. - Page 65-69

2 Ignatyev I., Trombitsky I. Genetically modified organisms and biological safety insurance. Kishinev: Ecorange Bendery, 2007. Page 60

3 Kuznetzov V.V., Kulikov A.M., Mitrokhin I.A. Tsydendambayev V.D. GMO and biological safety/M: EkoSinform, 2004, No. 10. – Page 60

4 What is the GMO and what are they produced for? // GMO – a zone of a high risk / Fund of integration of ecological culture, Alma-Ata, 2003. – Page 52

5 Ermishin A.P. Genetically modified organisms: myths and reality//Minsk: Technology, 2004. – Page 116

6 GMOs: control over society or public control/M: E.K. "desert-candle", Alliance CIS "For biosafety", 2005. – Page 198

7 Zones, free from GMO, under V. B. Kopeykina/M edition: Ãåîñ, 2007. - Page 106

8 Global Status of Commercialized Biotech/GM Crops: 2006 / http://www .isaaa.org (date of the address 20.01.2014)

9 The Kartakhensky protocol on biosafety to the Convention on biological diversity//http://www.biodiv.org (date of the address 22.01.2014)