Effects of Major Mineral Components of the Oral Liquid on the Teeth Caries in Children with Connective Tissue Dysplasia Syndrome

Authors: Avdusenko M.V., Bogdanova T.L.

Donetsk National Medical University named after M.Gorkij, KrasnyjLiman

Key words: children, oral fluid, calcium, magnesium, enamel resistance, undifferentiated connection tissue dysplasia

Introduction: The teeth caries resistance can be connected with the anatomical constitution of enamel, determining change of it’s main characteristics (acidoresistance, permeability, microhardness). Mineralization property is distinguished between many characteristics of enamel structure, having influence to it’scaries resistance. Magnesium has a direct influence on mineralization of organic bone matrix, collagen formation, functional condition of the bone cells, vitamin D exchange, and growth of hydroxyapatite crystal. In the context of physiology up to 53% of magnesium is concentrated in the bone tissue, dentine and enamel of teeth. Magnesium takes a significant role in formation of a normal structure of connection tissue. One of causative factors of connection tissue dysplasia formation is a dyscrasia.

Aim of study. To determine a content of mineral components in the oral fluid of children having undifferentiated connection tissue dysplasia syndrome and to reveal it’s connection with the teeth enamel caries resistance rate.

Materials and methods. 50 children at the age from 10 to 12 years were explored. Concentration of calcium and magnesium in oral fluid was determined by means of biochemical studies. The teeth enamel caries resistance was determined using enamel resistance test of Okushko V.R. Statistical data processing was performed by means of Statistica 6.0 and StatPlus 5.9 packages. Children were divided in two groups: the I group – the main group (with undifferentiated connection tissue dysplasia syndrome, 30 people) and the II group – the control group (conditionally healthy children, with a high caries resistance, 20 people).

Results. Average results of the mineral components were considerably less in the main group, than in the control group: concentration of Ca-0,88 mmol/l and 1,23 mmol/l correspondingly, Mg – 0,25 mmol/l and 0,44 mmol/l. Average results of the enamel resistance test were 5,83 and 4,15 scores in the main and control groups correspondingly. The results of calcium concentration in oral fluid of the main group compared with the control one were reduced for 28,5 % , and magnesium content – less for 43,2 %. The results of enamel resistance test showed that the results of the main group are for 28,8 % lower than in the control one.

Conclusion. Concentration of calcium and magnesium in the main group are in deficit and children of this group need a correction of specified microelements content. Insufficient quantity of calcium and magnesium content in child’s organism leads to enamel dysmorphology. This has a negative influence to the teeth enamel resistance.