Babich I.A., Lebedeva O.M., Zolotareva M.A., Mihaylova E.A., Luzin A.V.

State Institution «Crimea State Medical University named after S. I. Georgievsky»

CHRONIC INFLAMMATIVE-DISTRUCTIVE DISEASES GASTRODUODENAL ZONE IN CHILDHOOD: CHARACTERISTICS FEATURES OF THESE PATHOLOGY IN PRESENT DAYS

Actuality: Every year in Ukraine, there are records of increased pathology of gastroduodenal zone in children with prolonged, recurrent, complicated course, indicating lack of knowledge of all aspects of the disease and requires further study of the problem.

The aim of our study was to determine characteristics of a chronic erosive -ulcer diseases in childhood, given endoscopic picture, age and sex of the child, as well as duration.

We analyzed the case histories of 32 children with uncomplicated peptic ulcer and duodenal ulcer in stage I (exacerbation), and 47 patients with chronic erosive gastroduodenitis (EGD) in the acute stage, were treated in the department of gastroenterology in 2nd hospital, Simferopol from the period of 2010-2012 years. Verification of the diagnosis was based on complaints, anamnesis vitae and morbi, clinical examination, as well as additional methods of examination esophagogastro-duodenoscopy (EFGDS), bacterioscopic and breathing techniques (Helik test) to detect Helicobacter pylori (HP) and intragastric pH-metry.

Analysis of the data is as follows; Ulcer: girls 7-10 years in 9,4% of cases, between 11- 17 years old 37,5%,  boys: 7-10 years in 12,5% of cases, from 11-17 years in 40,6%. EGD: Girls 7-10 years in 8,5% of cases, 11-17 years in 46,8%, boys from 7-10 years in 12,8% of cases, between 11-17 years – 31,9%.

Research results shows that in most cases "fresh" ulcerative defect was of average size (0,3-0,5 cm) and was often localized: on the frontal bulbs of duodenum in 40,6% of cases, on the back - in 34,4%, on the side - in 15,6%. Children with EGD dominated blemishes from 0,1-0,3 cm in front of the bulbs duodenum in 25,5% of cases, the greater curvature of the stomach - in 19%, in the antrum in 14,8% of cases.

Duration of duodenal ulcer in childhood in most cases is up to 1 year from the initial presentation of the disease in children with gastroduodenitis - 1 to 3 years.
In 68,3% of children with ulcerative-erosive changes of gastroduodenal mucosa by HP infection presented II degree, at 16,5% - III degree, at 15,2% - I degree.

Given the findings of our study, we arrived at the following conclusions:

1. Duodenal ulcer was common in boys of high school ages, and gastroduodenitis - girls of the same age.

2. "Fresh" ulcerative defects were more of average sizes ranging from (0,3-0,5 cm) and located on the front of the duodenal bulb.

3. Erosion in the majority of cases occurred in the greater curvature of the gastric mucosa with size between 0,1-0,3 cm.

4. Contamination of gastroduodenal mucosa by HP in most cases is of II degree.