Irza O.L., Nepreluk O.A., Kushnir K.G.

Crimea state medical university named after S. I. Georgievsky, Simferopol.

 

The influence of syndrome of intolerance to acrylates in orthopedic patients on microbiological spectrum of oral cavity.

 

     One of the most important problems in modern prosthodontics is the problem of intolerance of materials used in proshtetics: in particular plastics.        We studied the microbiological total microbial count and persistent

 dysbiotic processes, increase anaerobic and aerobic reduction.

      The problem of intolerance to the materials used in medicine remains today one of the most  relevant.

      During the intolerance to acrylic plastic because of allergic stomatitis the patients complaint of impossibility of use or complicated use of removable prostheses because of constant feeling of burning in the mucosa of protheses area. Feeling of buring is more expressive on maxilla than in mandible. Hyposalivation make hard to use the protheses and make the clinical picture worse. The remove of protheses eliminated the subjective feeling.

      One of the most important problem is the problem of intolerance to the materials used in medicine.

    Simultaneously with the increase of the level of people using dental prosthesis. Increased the level of patients who can not use them for various reasons.
     In case of intolerance because of allergic stomatitis  on acrylic resin, patients complain of inability or difficulty in use removable dentures due to constant burning sensation is more pronounced in the maxilla than the bottom, which is , apparently , with the buffering properties of the mucous membranes of the upper jaw prosthetic field.
Materials and methods
     Comprehensive evalution and treatment of patients in need of orthopedic treatment with the use of removable plate dentures, conducted at the Department   of Proshtetic Dentistry Medical Center CSMU. Were examined 45 patients(including women 23; men – 22), which were established partial dentures of material “Ftorax”.These patients were treatment group(aged 45-75 years).

 The composition of the control group consisted of 40 patients between the ages of 25-65 years.   

Comprehensive evalution of patients conducted by  collection the  medical history, examination of the oral cavity and periodontal examination of alveolar bone in the area of ​​missing teeth. This carried out by the clinical and labaratory methods of examination, formulation of diagnosis.

     Mucosal scrapings of the oral cavity carried out by standard tampon

of  company “Sarsteds”(Germany), that allowed to increase the time of transportation in bacterial labaratory.

      Microbiological observations include the determination of total bacterial count by colony counting .

    In the analysis of the total number of microbial (TMC), and the ratio of aerobic and anaerobic  flora in the study of scrapings of the oral mucosa revealed that the patients after orthopedic prostheses removable plate dentures from acrylic plastic syndrome who developed intolerance to acrylates TMC has increased by 25 % (P<0,01) and was 1,5±0,08 conv.  u under the control of 1,2±0,07 conv. u with statistically significant(P<0,05) decreased by 22,2 % and the number of aerobic flora with a high degree of reliability growth of anaerobic flora(P<0,001)

 

Conclusions

1.After installation of removable plastic processes, made from acrylatic plastmas developed the syndrome of intolerance, which accompanied by inflammatory processes in peridontal tissues.

2. The syndrome of intolerance to acrylates accompanied by increase the level of total bacterial count comparably to control from 1,2 u. to 1,5 u.

3. The syndrome of intolerance accompanied by expressive disbiotic processes, developed prevalence of anaerobes.