Kushnir K.G, Irza O.L., Nepreluk O.A.

Chair of Dentistry (Postgraduate Education Division)

SI Crimea State Medical University named after S. I. Georgievsky

Impact of fixed implant-supported prostheses materials on biomedical measurements of mixed saliva.


The usage of dental implants expanded indications to restoration of teeth alignment defects with fixed implants, which gives us possibility to perform balanced prosthetic repair without teeth dissection. The material compatibility condition becomes the most primary problem for implants and tooth prosthesis made from different alloys. This article is related to optimization of the fixed implant-supported prostheses constructional materials choice.


53 persons were selected for carrying out of investigation. Besides 15 almost healthy persons (norm) were examined. The first group of 38 persons was composed of those whom were made the prosthetic appliance with PFM prosthesis based on cobalt-chrome alloy (Duceram). The second group of 15 persons was composed of those patients whom were made the prosthetic appliance with the usage of nonmetal ceramic dental prostheses. Prosthetic alignment was carried out by two stage implant procedure using U-Impl endosteal titanium screw implants with the further restoration using different permanent constructions.


Inside the investigated groups were segregated 2 subdivisions (19 persons in the first group and 8 persons in the second group), which were everyday intramuscular injected in gluteus with 1 ml single-dose of the Erbisolum immunomodifier and antioxidant. The duration of therapeutic course comprises of 10 days.


Antioxidant potency of mixed saliva was measured by the property of biomaterial to inhibit oxidation-reduction rate of Fe(2+)-2,6 - dichlorophenol-indophenol (DCPIP) system.