Kazinina E.N.,
Bobkova S.A., Makarenko V.N.
Crimea state
medical university named after S. I. Georgievsky, Simferopol.
Etiopathogenic approaches to treatment the traumatic
osteomyelitis of mandible
Last years the implantology precipitously
progresses. The achievement of expected results leaded to new issues emergence about used materials.
Although the orthopedic
treatment is very important, should take into account that during the treatment
foreign bodies entered into the oral cavity and located there for long time,
these foreign bodies from the materials that do not suited to the human body.
The article assessed the
efficiency of treatment of patients with traumatic osteomyelitis of mandible. Therapeutic complex include
antioxidant (erbisol) and osteoplastic material doped with silver (biomin GTLS)
Key words: traumatic osteomyelitis of the mandible , disorders of
redox processes, antioxidant, antimicrobial and osteoplastic local therapy.
The preparation “Erbisol”
is immunomodulator, reparant, and adaptogen. He has effect of activation of recovery processes, increase the
functional activity of tissues and organs. The complex treatment of destructive
complicantions after fractures of mandible should contribute the optimization
the processes of reparation and complete eliminating of defect, developing
after sequestration. For this used osteoplastic materials , having stability to
inflammation and the ability to arrest the local inflammatory reactions.
The purpose of our
investagation is to show the etiopathogenic approaches to treatment of
osteomyelitis of mandible by including in complex of treatment the
preparaions with antihipoxant ,
antibacterial and local osteoplastic effects.
Materials and methods
Were examined 58 patients with
osteomyelitis. In additional were 27 people as control group. All examinated
were divided into 2 groups: 1 group(27 patients) – healthy people in age 18-25
with no diseases. 2 group (the main) included 2 subgroups. In first (subgroup
A) patients with traumatic
osteomyelitis of mandible, received traditional complex treatment(with preparation
tocopherol ) with local use the hydroxyapatite. In second group( subgroup B) 26
patients with traumatic osteomyelitis of mandible also used Erbisol.
The patients with traumatic
osteomyelitis of mandible carried out immobilization of mandible. In remission
phase carried out surgical treatment phase(sequestrectomy). During the
operation the formed defect of bone filled partly (2/3) by sintetic
osteoplastic material. After
impregnation of the material with blood he cover all volume of defect.
Results and discussion
During the first month
after prosthetics the changes had statistically insignificant character in both
groups of observation.
The analysis of received
data has showed that agains the bahground of use the preparation Erbisoland
osteop material the inflammatory reactions occurred expressively and poetry at
an earlier date.
The dynamics of recovery
indexes had main value for us because it allow to estimate the level of
efficiency of carried out operation(sequestration) and the quanity of
developing secondary immunodeficiency which had the patients with traumatic
osteomyelitis of mandible.
In this way the indexes of
complex investagation and treatment in
patients with traumatic osteomyelitis has showed , that the disease
ocurs against the background of local hypoxia. The learning of efficiency of
tocopherol and erbisol has showed the advantage of erbisol.
Conclusions
1.
The use preparation “Erbisol” significantly decrease the terms of adaptation of
orghanism after proshetics in all group of observation.
2.
The immediate
and long-term results of treatment of patients with traumatic osteomyelitis of
mandible testified, that the most effective is to close osseous defect by
bioresorbable osteoplastic material , doped with silver with next
administration immunomodulator and
antioxidant Erbisol in postoperative perioud.
3.
The use the
immunomodulator Erbisol allow to reduce drug load on patients body at the
expense of it unique features.