УДК 619:636.7:619.9

Sickness Rate and Treatment of the Chlamydia Infection of Dogs in the City of Kostanay

Annotation

Kulakova L. S.– associate professor of the department of veterinary Kostanai State University. A.Baitursynov

Tokareva К.– 5th year student the department of veterinary medicine faculty of veterinary medicine and animal breeding technology

Annotation

The statistical data of the chlamydia infection sickness rate of dogs depending on sex, age, and the time of the year from 2010 through 2013 are provided in the article. Also, an effective therapeutic program in treating this disease is proposed in the article.

Among numerous quadrupedal friends of humans, domestic dogs and cats are considered the most faithful and loyal in their own right that amount, nowadays, to more than a billion. And today, there are pets in almost every single house [1, 2, and 3]. Animals tend to be down by many diseases, including the chlamydia infection, which has infected about 18-38 % of dogs [4].

The chlamydia infection is an acute or chronically passing zoonotic disease, characterized by an infection of the genitourinary system, a development of keratoconjunctivitis, rhinitis, and pneumonia [5].

Telling that the chlamydia infection of dogs and cats is rarely seen is quite premature, because in recent years, with the improvement of the laboratory diagnostics methods, chlamydiae are found more often. Nowadays, some of the leading foreign producers of vaccines, for instance, in France, include an anti-chlamydia infection component in a vaccine for cats [6]. Thus, the research on the chlamydia infection sickness rate and treatment of carnivores is of current interest.

The goal of our research was to find an effective therapeutic program in treating the chlamydia infection of dogs.

Proceeding from the goal we have put the following objectives:

1. Study the chlamydia infection sickness rate of dogs depending on sex, age, breed, and the time of the year.

2. Test the therapeutic program of the chlamydia infection of dogs which consists of a Polioxidonium immunomodulator and antibacterial complex based on a Dorinum antibiotics.

The research was being carried out at the KSU Veterinary Clinic, 99/1 Mayakovskiy Street, Kostanay. The material of the research was based on the animals diagnosed with the chlamydia infection, verified at the RGP "RVL" laboratory, 43 Naberezhnaya Street, Kostanay. The statistical processing of the sickness rate data have been done with the help of ambulatory journals.

In the KSU Veterinary Clinic from 2010 to 2013 years, 476 animals were ambulatorily accepted with the diseases of the reproductive system. Different diseases had been discovered both males and females: andrologic (phimosis, inflammation of testicles, inflammation of prepuce, venereal sarcoma, cryptorchism, orchitis) - 210 animals (diagram 1); gynecological (endometritis, pyometra, salpingitis, ovarian cyst). - 266 animals (diagram 2).

Carrying out the data analysis of the diagram 1 we see that phimosis makes up 7%, inflammation of testicles 5%, inflammation of prepuce 67%, venereal sarcoma 6%, cryptorchism 7%, and orchitis 8%. Among the andrologic diseases the inflammation of prepuce takes the first place which was found in 140 dogs, among which, there were 50 animals with the chlamydia infection.

Carrying out the diagram 2 analysis we see that endometritis makes up 50%, pyometra 30%, salpingitis 7%, ovarian cyst 13%. The diseases accompanied by the chlamydia infection were found in 117 animals, which amounted to 44%.

The season dynamics of the chlamydia infection of dogs is shown in the (diagram 3), which points out that the chlamydia infection occurs in all the times of the year. In summer - 37%, in fall - 24%, in winter - 17%, in spring - 22%. Most of the percentage of the diseases is noted in summer (37%), which is, in our opinion, connected to exogenous and endogenous factors. In spring and fall with a drop of animal resistance in these times of the year.

The dependence of the chlamydia infection sickness rate based on animals' age (diagram 4), has been distributed the following way: up to 1 year - 19,4%, 1-5 years - 44,5%, 6-10 years - 19,4%, 11 years and older - 16,7%. Most of the percentage of the sickness rate in the age group 1-5 years is connected to the sexual activity of this age group.

As for the interconnection of the chlamydia infection and the breed composition of dogs, we see that it occurs among all breeds and crossbreeds of dogs, but usually this disease is immanent in such breeds as German Shepherd, Dachshund, and Boxer.

All the animals with the prepuce inflammation were clinically examined as well as have gone through a mandatory laboratory examination in order to find the cause of the chlamydia infection, in the Regional Veterinary Bacteriological Laboratory of the city of Kostanay. Among 140 males with the prepuce inflammation, there were only 50 dogs with the chlamydia infection which was confirmed at the laboratory, and these animals, subsequently, have become the material for our research. All the animals have been divided into two experimental groups based on the principle of analogues with 25 animals in each group.

The animals of the first group have got the treatment that is used in city clinics.

1. The antibiotic Ceftriaxone with a dose of 20-100 mg/kg, intramuscularly, once a day, a course of 10 injections.

2. An antibacterial medicine Metronidazole, 25 mg/kg, twice a day, inside, a course of 10 days.

The animals of the second group have got the treatment made by us:

1. Dorinum with a dose of 5 mg/kg based on the physiological solution, intravenously, once a day, a course of 3 injections starting on the 5^th day of treatment.

2. For the stimulation of the immune system – the immunomodulator Polioxydonium with a dose of 0.2 mg/kg, intramuscularly, once in 24 hours, a course of 11 injections.

3. Locally developing trays with 0.02 dose of furacilin solution

The difference in the treatment programs was in using of the antibiotics and the antibacterial medicine from different groups and our inclusion of the immunomodulator Polioxydonium in our treatment program.

Polioxydonium was used the following course: the first week, intramuscularly, once a day, with an interruption on the 3^rd day, and the next 10 days, the injections were done in 24 hours with the same dose.

As a result of the conducted treatment all the animals of the experimental (the second) group have gotten completely healthy (confirmed in a laboratory), relapses of the disease and the complications by the staphylococcus infection have not been observed in any of the 25 animals. Among the 19 animals of the first group, the relapses of the disease have appeared after a week of the treatment course. After a repeated laboratory examination there were 6 animals only with no chlamydia infection which amounted to 24%.

Our experiments were carried out in industrial conditions and it lets us make a following conclusion

1. The chlamydia infection has a widespread occurrence in the city of Kostanay and amounts to 36% in males, and 44% in females.

2. The most quantity of the animals with the chlamydia infection occurs in the summer period, 37%.

3. Most of the time, the animals from 1 year to 5 years are affected by the chlamydia infection.

4. The chlamydia infection treatment program which includes the immunomodulator Polioxydonium in its composition, 4.2 times more effective than traditional therapeutic programs.

Practical propositions

For the treatment of the chlamydia infection among dogs, we recommend for practicing veterinary doctors to include in their treatment program – Polioxydonium. Scheme of use: in the first week intramuscularly once a day, with an interruption on the 3^rd day, and the next 10 days, the injections were done in 24 hours with the same dose.

Literature

1. Baranov A.B. The Health of Your Dog. – RIMEKS. – 1992. p. 432 – ISBN: 5-86452007-1

2. Belov A.D., Danilov E.P., Dukur I.I., and others. Diseases of Dogs. – M. Kolos, 1995 – p. 272.

3. Bratyukha S.I., Nagorny I.S., Revenko I.P., Shevtsov A.A., Ptitsyn A.K. Diseases of Dogs and Cats. – Kiev: Publisher “Vishcha Shkola”, 1979. – p. 232.

4. [http://www.kfrt.ru/ru/lib/issue/f16/o157/]

5. [http://vetclinic.com.ua/news/2009-12-30-17]

6. [http://www.puppy-dog.ru/vet/209.shtml.htm]