Биологические науки /6. Зоология

Khabibullin R.M., Khabibullin I.M., Bakirova A.U.

Bashkir State Agrarian University, Russia

Influence Pantokrin mice blood

during exercise

For selected studies mice weighing 22-24 g, which was formed of six groups of test animals. The mice of the first group asked the water; the animals of experimental group – pantokrina infusion at a dose of 2 l of 1 to 7 days, 4 to 8 l to 14 l and 6 day 15 to day 21. During experience physical performance was assessed by the swimming test according to the method of "forced swimming". Changes in the blood were studied by conventional methods in biology [1, p. 56]. After 16 days after the start of the experiment duration diving sharply increased in all groups, especially the figure was significant in the experimental group received №1 after exercise tincture pantokrina. Indicators swimming duration №1 in the experimental groups were higher than this figure compared to the control group to 97.0 sec, respectively. Subsequent definitions duration voyage maximum performance we noted 26.12.2013 year. The indicator had a maximum difference of the experimental group and the control group №1 in 267.0 seconds. The highest absolute increase in swimming activity we observed in the experimental group №1, it amounted to 371.40 seconds, while the lowest - in the control group – 106.30 seconds.

Morphological changes in the blood, and we have noted in the mice of the experimental group №1, treated after exercise tincture pantokrina regarding blood morphology parameters in the control group. Included Quantitytion of red blood cells prior to the experimental studies in mice of experimental group №1 and the control group had a slight difference, and conform to the norms [2; 3]. After completion of the experiment the mice of the experimental group №1 erythrocyte count was 7.41 x 1012 / L, that exceed the number of erythrocytes in the control group of 1.40 x 1012 / L.

Changed and hematologic parameters in the application of tincture pantokrina. The content of hemoglobin in the experimental mice in both groups in the beginning of the experiment had no significant difference, and is within the normative parameters. After carrying out an experiment with high physical activity in mice of the control group, we note the lag in the amount of hemoglobin at 22.0 g / l, relative to the mice of the experimental group 1 № treated after exercise tincture pantokrina whose active component was 168 g / l at the end experiment [4].

The number of leukocytes in the beginning of the experiment the mice of the control group was significantly higher at 0.24% than that of the experimental group mice №1. At the end of experimental studies the number of white blood cells in the control group of mice was 8.81%, and they beat on this indicator mice of experimental group №1 3.31%, indicating that violations of the physiological state and the negative processes in the body of animals in the control group.

When counting the lymphocytes prior to the start of the experiment, we found that the number of both groups is a slight difference, and within the legal parameters. After the experience of this component of blood cells in the experimental group №1 was 71.98%, which is higher than in the control group to 9.58%. This indicates violations of the physiological processes associated with the development of hypoxia and violation of metabolic processes.

On the development of disorders in metabolic processes in the end of the experiment in the control group, in which the experimental mice after exercise did not receive adaptogens, and demonstrates a shift "right", ie predominance in the number of segmented neutrophils [5].

In mice, the experimental group №1 number of segmented neutrophils after the experiment was 15.08%, at the same time reached 25.10% in the control group, the number of formed elements of the data, which is 10.02% higher than the rate in the experimental group. As a control group of mice we marked superiority over the animals of the experimental group №1 content of eosinophils and basophils by 1.59% and 0.97%, respectively. What is also indicative of violations of physiological functions in the body of the mice in the control group, and at the same time the content of the above formed elements in the treated group №1 was 0.42% and 0.49%, respectively.

Conclusion: pantokrin application helps to increase swimming activity, a change in blood morphology and some biochemical parameters.

References:

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5. Хабибуллин Р.М., Фазлаева С.Е. Сравнительное испытание адаптогенных свойств настоек экстрактов Левзеи сафлоровидной и пантокрина // III Съезда фармакологов и токсикологов России. Санкт-Петербург, 2011. С 556.

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