Медицинские науки/ 1. Акушерство и гинекология

Medical sciences / 1. Obstetrics and Gynecology

Syusyuka V.G., Peycheva E.V., Gorbacheva S.V.

State Medical University of Zaporozhye, Ukraine

Maternity hospital No. 9, Zaporozhye, Ukraine

condition OF sympathoadrenal system and magnesium LEVEL OF pregnant women regarding psychological component of gestational dominant

Key words: pregnancy, psychoemotional state, anxiety, sympathoadrenal system, magnesium

State of the pregnant woman can have significant influence on features of the prenate psychological functions which are being formed and therefore it can considerably determine his life scenario [3]. Prenatal negative effects have the strongest destructive influence. If during pregnancy mother had severe stress, intensive anxiety or depression or took glucocorticoids this could lead to reduction of weight and body size of fetus by delivery, decrease of hippocampus size and cellular damages in the brain [10].

Lack of magnesium during pregnancy can cause undesirable consequences both for the mother and fetus: abnormality of fetus implantation, calcinosis of placenta (consequence of calcium metabolic imbalance in conditions of magnesium deficit), long-term threatening miscarriage, premature delivery, weak labour activity, abnormal cervical dilatation during expulsion of fetus, symphysiopathy, symphysitis, preeclampsia and eclampsia [2, 4, 5, 7, 12].

Object of investigation: to estimate mutual influence of sympathoadrenal system, the level of magnesium and psychoemotional state of the pregnant women.

Group of examined persons and methods of investigations 30 Pregnant women were examined in II and III trimesters (27.9±1.73 weeks). Average age of the women under examination was 26.23±1.50 years. Psychoemotional state of the pregnant women was estimated based on structured interview, questionnaire and psychological tests (Spielberg-Hanin tests, test of the pregnant woman attitude, Personality Questionnaire of the V.M. Bekhterev Institute (PQBI) [1, 3, 8, 9]. Concentration of magnesium was determined by set of instruments for diagnostics in blood serum. Level of dihydroxyphenylalanine (DOPA), dopamine (D), noradrenaline (N) and adrenaline (A) was defined in urine collected during 24 hours by means of unified method of Matlina E. Sh. and co-authors [6].

Results of discussion and conclusions

Based on estimation of magnesium level and indicators of sympathoadrenal system (SAS) of pregnant women regarding psychological component of gestational dominant (PCGD) there was stated that level of noradrenaline of pregnant women with PCGD different from the optimal type was statistically higher (p < 0.05) than the level of pregnant women with optimal type (41.73 ± 21.48 and 18.31 ± 2.32 mcg/day, correspondently).

During investigation of magnesium level of pregnant women with PCGD different from the optimal type in 64.7% of cases there was deviation from the reference values that is in 2.8 times higher than the appropriate indicator of pregnant women with optimal type of PCGD. Estimation of hormones reflecting condition of SAS regarding magnesium level permitted to state that level of noradrenaline of pregnant women with optimal type of PCGD was statistically lower (p < 0.05) than noradrenaline level of pregnant women with PCGD different from optimal type both with low and high level of serum magnesium. Results of performed investigation show correlation of SAS indicators, particularly of noradrenaline and magnesium level which depend on psychoemotional state of women during pregnancy.

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