Usage of microimplants in presurgical orthodontic treatment of children with bilateral cleft lip and cleft palate .

 

MD., professor, Honoured Science Worker of  Republic of  Kazakhstan T. K. Supiyev1, MD. N. G. Negametzyanov1 ,  candidate of medical science E.C.Katasonova1,  doctoral candidate E.M. Kozhabekov2

 

1 Kazakh National Medical university named  by  S. D. Asfendiyarov,  Almaty city

2 International Kazakh-Turkish University named by H. A. Yassavi, Turkestan city.

 

Abstract. There are three levels of intermaxillary bone deformation were observed in children with cleft lip and cleft palate. The patients with first and partially with second level of intermaxillary bone deformation have been prepared for heylo-and uranoplastics by palatine plates. For third level of intermandibular bone deformation to fix nonremovable orthodontic devices the microimplants were used. It was possible to get the full butt (end) contact between intermandibular bone and fragments of upper jaw and it was made optimal conditions  for surgical operation.

 

Key words: cleft lip (cheiloschisis) and cleft of palate, intermaxillary bone deformation, orthodontic treatment,  cheiloplasty,  uranoplastics,  microimplants.

 

Introduction.  The most severe form among of  congenital cleft lip (cheiloschisis) and cleft of palate is congenital bilateral cleft lip (cheiloschisis) and palate which can be meet in 15-25%  of cases [1,2] They are caused a number of difficulties in presurgical preparation period of patients.

         In order to prevent the development of secondary deformities of maxillofacial part the specialists [3,4] recommend to use an early presurgical correction of fragments location of the upper jaw. It is reputed that early orthodontic treatment of these children allows to normalize the process of feeding and to prevent secondary deformities, progressing in the growth process, to eliminate that in the future requires a long multistage complex treatment.    

  To treat such type of the children in presurgical  period specialists more often use removable orthodontic appliances. In these cases, treatment is characterized by long periods and it depends on many factors: the magnitude of diastase, the timing of treatment beginning, the child habituation to the apparatus and etc. The lack of these devices are: poor fixation in edentulous jaws, the necessity for frequent doctor visits and the necessity for repeated replacement of apparatuses. As a result, it leads to a considerable duration of treatment, and it is not always possible to get the maximum convergence of fragments of the upper jaw.

For the present time more and more researchers and practitioners, orthodontists come to the opinion about necessity to develop the new technologies during an early stage of complex treatment of the children with congenital cleft lip and palate. Particularly,  the use of removable orthotic devices with intraosseous fixation.   

In 1990, in press Latham R.A. and Millard have described a modified non-removable orthotic device for repositioning of intermaxillary bone in children with bilateral cleft lip and palate [5]. Recently it was found that the microimplants, in addition to chewing can successfully carry the burden of the orthodontic attachments components (springs, elastic and etc.), remaining motionless, and without loss of osseointegration [6]. These data allowed us to expand the indications for implantation and in the using of orthodontic technology during the treatment of children with cleft lip and palate beginning from an early age.

The purpose of the study is an explanation of presurgical orthodontic training of the children with congenital cleft lip and palate by using of microimplants.

Material and methods. In Almaty center of children rehabilitation of congenital and hereditary pathology of maxillofacial 23 children with bilateral cleft lip and palate were under our observation. And these children were prepared for surgery orthodontic treatment by using microimplants. There was two compared groups of patients with congenital bilateral cleft lip and palate with 25 patients in each: the first – operated patients without presurgical orthodontic preparation, the second - operated patients after presurgical orthodontic training  by removable orthodontic appliances.

The study of diagnostic models. The diagnostic model of all 73 patients was studied by conventional methods in our modification. We proposed the modification which will minimize errors, facilitate the measurement process and ultimately it has a positive effect on the choice of method of used early orthopedic treatment. The method includes: making a stone cast by the model of the upper jaw of the child with congenital bilateral cleft lip and palate. The alveolar and palate processes borders,  an intermaxillary bone and vomer borders have been marked by marker on stone cast and  reference points are fixed. The model was photographed by digital camera with a rigid fixation in the standard position. The received pictures were loaded in the computer, where the graphic form of the alveolar processes, palatal processes, intermaxillary bone and the vomer have been received by AUTOCAD program where were marked reference points and the linear and angular measurements have been produced. In the graphical representation the area of splited fragments, the length of alveolar processess, width of cleft palate along the whole length, the longitudinal dimensions of crevices, the position of the fragments of the upper jaw by sagittal were studied. The results were recorded in a specially designed patient`s card.

As a result of studies there were observed  different degree of deformation of the side fragments of the alveolar process of the upper jaw, protrusion of  an intermaxillary bone, the angle of deviation of the midline. Depending on the severity of the deformation of the intermaxillary bone, we have identified three groups of the children with mild case, moderate case, and severe case of bones deformity.
        Computerized axial tomography was used during pronounced deformation of the upper jaw to plan the location of fixing elements of supramaxillary device.          Computerized axial tomography study
was made on the X-ray computer tomograph Somatom-CR (Siemens) according to the bone reconstruction program with high resolution (intersection gap is 2 mm, section thickness is 2 mm, the voltage is 120kV, current strength is 22 gPa).The study was made in a horizontal position of patient on his back. For fixation of an examined child`s head the following were used: standard stand support  behind his head and fixtures in the form of special pads and fixing tapes.

The studies of the upper  jaw were executed in axial and coronal projections with reconstruction of images in the sagittal plane.On the obtained sections anatomical formations of the upper jaw, the rudiments of teeth, vomer were determined optimally.

 The Surgical implant placement protocol for the creation of support of supramaxillary non-removable devices with intraosseous fixation did not differ from the standard methods of dental implantation. However, in the hard palate area the surgery was planned carefully and executed with great care. It was conditioned by the potential possibility of perforation of the nasal cavity wall and other anatomical structures. Therefore, installed implants in the hard palate were provided for short length (4-6 mm), which depended on the volume of available bone. As the support elements and fixing elements of non-removable orthopaedic devices with intraosseous fixation, we used the microimplants (Absoanchor, Dentos corporation, Dagu, Korea), designed specifically for use in orthodontics.    

     The depth of an  implant  immersion into the bone depended on the method of further fixing to it the wire. If it is directly fixed with hinges and screws, for convenience, the neck of the implant was placed at 1-2 mm above the surface of the bone. In the case of used a special  suprastructure to fix the wire, then the implant is completely immersed in the formed bone bed.
     

 Statistical  methods.  The research results were subjected to statistical analysis by using of parametric and nonparametric statistical methods.

The results and discussion. The clinical and biometric studies of children with congenital bilateral cleft lip and palate during  presurgical period revealed three level of  intermaxillary bone deformation  and the side fragments of the upper jaw.

In the first group of patients in the two cases, the maxillary bone was in the right position, and in 22 patients, the transverse size of the intermaxillary bone was 15 mm, protrusion – up to 7 mm, the angle of deviation from the median line – from 0 up to 5 degrees, the displacement by the vertical plane was up to 2 mm. The distance between the front edges of the side fragments of the alveolar process of the upper jaw is up to10 mm. The width of the defect on the border of hard and soft palate was 14,8 ± 1,0 mm (Fig. 1a, b).


à) plaster cast                                      b) schematic mo

 

Fig. 1 – The general view of plaster cast (à) and its` schematic image (b)

in patient who was delivered to the hospital (1level)

 

The second level of an intermaxillary  bone and the side fragments of the upper jaw were found in 26 patients. They had a transverse dimension of the intermaxillary bone -20 mm, protrusion - from 8 mm up to 15 mm, the angle of deviation from the median line - up to 10 degrees, displacement from the vertical plane - from 2 up to 4 mm. Distance between the front edges of the side fragments of the alveolar process of the upper jaw was up to 15 mm. The width of the defect on the border of hard and soft palate was 19,3 ± 1,0 mm (Fig. 2a, b).

 

                   à) plaster cast                       b) schematic model image

 

Fig. 2 – The general view of plaster cast (à) and its` schematic image (b)

in patient who was delivered to the hospital (2 level).

 

The third level of an  intermaxillary bone deformation and the side fragments of the upper jaw were found in 23 patients. They had a transverse dimension of the intermaxillary bone up to 25 mm, protrusion -from 16 mm and more, the angle of deviation from the middle line - from 11 degrees and more, the displacement by the vertical plane –from 5 mm and more. The distance between the front edges of the side fragments of the alveolar process of the upper jaw was up to 25 mm. The width of the defect on the border of hard and soft palate was 22,7 ± 1,0 mm (fig. 3a, b).

         à) plaster cast                    b) schematic model image

 

Fig.3  – The general view of plaster cast (à) and its` schematic image (b)

in patient who was delivered to the hospital (3 level).

 

The division of patients with congenital bilateral cleft lip and palate into 3 groups before the treatment had a practical importance, which was taken into account when planning the treatment. Usually, we took to the treatment patients with the first and partially with second part of deformation degree of  Intermaxillary Bone, by using of removable orthodontic appliances [7]. In the case of  the intermaxillary bones deformations of the third degree the presurgical preparation of patients was performed by using of innovative technologies (non-removable devices, fixed microimplants, or use of microimplants).
     Clinical application of microimplants. All patients (23 children) with congenital bilateral cleft lip and palate with third degree of  intermaxillary bone deformation  the presurgical orthodontic treatment was executed by using of microimplants. At the begining, the microimplants have been used in 6 patients for intraosseous fixation  of supramaxillary non-removable orthodontic appliances (Fig. 4). Others 17 children with such pathology used the microimplants as supporting elements of orthodontic appliances (Fig.5).
       Presurgical  orthodontic preparation of patients was carried out in several stages. At the beginning  the plaster casts of the upper jaw have been taken from children at the  children dental clinic. After that, the models of  jaws were under preparation. Analyzing the results data  of diagnostic models of the upper jaw and the parameters of the computer-tomographic study the place of installation microimplants was determined.

      Within children's clinic conditions of maxillo-facial surgery under the general anesthesia, 6 patients have been installed by supramaxillary non-removable devices that are fixed to the bone by using of microimplants (Figure). For this purpose the holes in the projection angle of 45 °C to the top of the comb of the alveolar process were prepared beforehand on the fixed fragments (two side and maxillary bones). At the same time the both sides fragments were connected by a V-shaped orthodontic screw for expansion of the side fragments of the upper jaw. This structure of the apparatus used for the expansion of the side fragments of the upper jaw and for repositioning the intermaxillary bone in the correct position, forming the alveolar arch.

 

                             

                         4                                                                                 5

Fig. 4 -patient À-v Ñ. ,  4 months., bilateral cleft lip and palate after fixation supramaxillary non-removable device to the upper jaw fragments and to the intermandibular bone by microimplants.

 

Fig. 5 -  patient V-yev, 5 months., bilateral congenital cleft lip and palate after installation of the microimplants to the upper jaw fragments and to the intermandibular bone for orthodontic treatment.

The next step was to adapt the child to the apparatus and the adjustment

 of its feeding, training the mother for hygiene care of oral cavity in child and apparatus.The location of microimplants in the side fragments of the upper jaw was monitored by panoramic radiographs. Depending on the children health status  the children were discharged from the hospital on 6-7 days after surgery under the supervision of orthodontist.
       After the child's adaptation to the device the screw is activated by 0.5 mm once in two days, with simultaneous activation of an elastic traction on one link in the three days. Taking into account the continued growth of divided alveolar process of  upper jaw
at length after cheiloplasty the fragments cleft of the upper jaw shouldn`t be  completely locked, leave the diastasis between them on the width of the temporary tooth. The duration of an active period ranged from 20 up to 30 days. One of the important step is the retentional period, which ranged from 15 up to 30 days. After the end of retentional period the device was removed, and primary cheiloplasty on both sides has been conducted immediately.

Last time we use microimplants in order to transfer separate fragments of the upper jaw and  shape them into dental arch in account with severity degree of an intermaxillary bone and side fragments of the alveolar processes of the upper jaw. Such early orthodontic treatment is one of the few samples of an innovative technology using  during  presurgical treatment of the children with congenital bilateral cleft lip and palate before surgical intervention.
If the microimplants were used without using of supramaxillary orthodontic apparatus the moving of the jaw fragments and the normalization of
dentoalveolar arch  have been occured during 1 month after the start of orthodontic treatment.

Thus, the deformations study of the alveolar and palatal processes of the intermaxillary bone and palate in children with congenital bilateral cleft lip and palate has allowed us to approach differentially to the various methods of presurgical preparation of children with such pathology. The literature data and our own research are allowed to emphasize if more time passes before the surgery without the orthopedic and orthodontic treatment, then the deformation of  the intermaxillary bone and vomer will be exacerbated.  It is occurs because of the  influence of tongue and nipple, which is especially noticeable with very severe  deformation of the intermaxillary bone and vomer. So which means that in children with congenital bilateral cleft lip and palate the deformity of the intermaxillary bone is increased by age, and it`s depends on the initial indexes of the disease severity (mild, mean, severe), and also depends on the ways of children preparation for the surgery in the presurgical period.

  The application of the microimplants within presurgical preparation of the patients with cleft lip (cheiloschisis) and cleft of palate plays the main role in the surgical rehabilitation and it helps to the surgeons to make primary surgery without any difficulties and also it has a positive effect on the healing of lips tissues.
For comparison characteristic of the results of the different methods of presurgilal preparation  of the children with congenital cleft lip and palate the  anthropometric studies of the jaws were done. (Table).

     

Table - Anthropometric data received from the jaws models of the children with  bilateral congenital cleft lip and palate, prepared for the surgery by different methods.

 

Age periods

 

 

 Distribution of the children by treatment methods

Without presurgical orthodontic preparation  (p=45)

Treated patients by T.V. Sharova`s method (p=48)

The patients treated by using of microimplants  (p=28)

Side of displacement  of the intermaxillary bone

On the side from the intermaxillary bone displacement

Total

On the side of  the intermaxillary bone displacement

On the side from the intermaxillary bone displacement

Total

On the side of  the intermaxillary bone displacement

On the side from the intermaxillary bone displacement

Total

1 month

8,5

±0,52

10,9

±0,42

19,4

±0,47

10,5

±0,83

11,5

±0,65

22,0

±0,74

8,4

±0,92

11,6

±0,87

20,0

±0,71

3 months

9,4

±0,95

12,1

±0,62

21,5

±0,81*

8,8

±0,70

10,9

±0,88

19,7

±0,79*

8,3

±0,93

11,5

±0,86

20,3

±0,89

6 months

9,8

±0,92

12,7

±0,74

22,5

±0,83*

6,4

±0,57

7,6

±0,62

14,0

±0,59*

1,2

±0,27

1,4

±0,32

2,6

±0,29*

12 months

8,1

±0,84

10,7

±0,88

18,8

±0,86

3,5

±0,39

5,5

±0,24

9,0

±0,31*

0,9

±0,17

1,1

±0,18

1,0

±0,18*

 

* The differences statistically are significant in comparison with indices, received from newborn  of 1 month (Ð<0,05).

 

As shown in the table, in patients of the comparable group with the growth of a child with congenital bilateral cleft lip and palate the defects between the intermaxillary bones and side fragments of the upper jaw increase and reach its maximum at 6 months. After cheiloplasty it was observed statistically unauthentic decrease of the bone defect.
    In patients who were prepared for surgery  with removable orthodontic devices, the bone defects statistically and significantly decrease from 22,0 ± 0,74 mm  up to 9,0 ± 0,31 mm, but the full
butt contact  between  the intermaxillary bone and side fragments of the upper jaw was not occurred.

             After  executed presurgical preparation with using  of non-removable supramaxillary devices fixed by microimplants, and also by microimplants it was reached the full frontal contact between the intermaxillary bone and fragments of the upper jaw, which was confirmed by static treatment of the material (P ˂ 0,05).
    For illustration we present the stages of complex treatment of the S.Yu-va patient (Fig. 6), who came to the clinic at 3 months of age. After third degree determination of the intermaxillary bone the presurgical patient preparation was carried out by using of the innovative technologies (non-removable supramaxillary orthodontic device, fixed by microimplants). Bilateral cheiloplasty was made at the age of 6 months and sparing palatoplasty-at the age of 1.5 years.

 

                                   À                                                               Á

 

                                                                                       Ã

 

 

 

                                        Ä                                                     Å

                                         

                                   Æ                                                             Ç

                                                                                                  

                                                                       È

  Fig. 6 -  Patient S.Yu-va, 3 months., diagnosis: Congenital  bilateral  cleft lip and palate (3 degree of the intermaxillary bone deformation):

À) Patient`s appearance when delivered to the hospital,

B)  Plaster cast of the frgaments of the upper jaw before treatment,

C)  The fitting of supramaxillary orthopaedic device on the plaster cast,

D) The fixation of supramaxillary orthopaedic device by microimplants to the jaw fragments,

E)  Intermaxillary bone status in patient  at the age of 6 months,

F)  The patient state after bilateral cheiloplasty,

G) Palate tissues status in patient at the age of 1,5 month before surgery,

I) Palate tissues status in patient at the age of 1,5 month after  palatoplasty,

J) Patient`s appearance S. Yu-va at the age of 2 years.

       Summary. The modern design of devices allows  to reduce presurgical preparation, to enter into the design active elements, to normalize the location of intermaxillary bone and  the upper jaw form, and without special difficulties to produce a primary surgery of cheiloplasty, after that the palatoplasty, accelerate the timing of complex rehabilitation of patients with such complicated pathology of maxillofacial area as bilateral congenital cleft lip and palate with good aesthetic results.

 

Literature.

 

      1. A.S. Artyushkevich, V. I. Phillipenko, L.S. Krishtopenko and others: New in the treatment of the cleft lip and . // Materials of IV congress of the dentists of Byelorussia: «Arrangement, prophylaxis, new technologies  and rehabilitation in dentistry». – Vitebsk, 2000. – P. 342344.

      2. E.S. Katasonova Substantiation of using new technologies at early growth of holiatry of the children with congenital bilateral cleft lip and palate: author's abstract of candidate dissertation  – Almaty, 2010. – P. 20.

      3. Turley P.K., Kean C., Schur J. et all.  Orthodontic force application to titanium endosseous implants. // Angle Orthod. – 1988. -  Vol.58, N 2. – P. 151-162.

     4. Gray JB, Smith R.  Transitional implants for orthodontic anchorage. // J Clin Orthod.- 2000.- Vol. 34, N 11.- P. 659-666.

      5. S.I. Blokhina, G.V. Dolgopolova, Medical and social rehabilitation of the children with congenital cleft lip and //Dentistry and baby`s health: thesis report of 1-st  Republic conference.– Ì., 1996. – P. 20.

      6. Millard D.R. Improved primary surgical and dental treatment of clefts / D.R. Millard, R.A. Latham // Plast. Reconstr. Surg. - 1990 - Vol. 86. - P. 856 - 871.

     7. T.V. Sharova, G. I. Rogozhnikov  Orthopeadic dentistry of infancy. – Ì.: Medicine, 1991. – 288 P.