Usage of microimplants in
presurgical orthodontic treatment of children with bilateral cleft lip and
cleft palate .
MD., professor, Honoured Science Worker of Republic of Kazakhstan T. K. Supiyev1, MD. N. G. Negametzyanov1
, candidate of medical science
E.C.Katasonova1, doctoral
candidate E.M. Kozhabekov2
1 Kazakh National Medical university
named by S. D. Asfendiyarov, Almaty
city
2 International Kazakh-Turkish University
named by H. A. Yassavi, Turkestan city.
Abstract. There are three
levels of intermaxillary bone deformation were observed in children with cleft
lip and cleft palate. The patients with first and partially with second level
of intermaxillary bone deformation have been prepared for heylo-and uranoplastics by palatine plates. For third level of intermandibular
bone deformation to fix nonremovable
orthodontic devices the microimplants were used. It was possible to get the
full butt (end) contact
between intermandibular bone and fragments of upper
jaw and it was made optimal conditions
for surgical operation.
Key
words: cleft lip (cheiloschisis) and cleft of palate, intermaxillary bone
deformation, orthodontic
treatment, cheiloplasty,
uranoplastics,
microimplants.
Introduction. The most severe form among of congenital cleft lip (cheiloschisis) and
cleft of palate is congenital bilateral cleft lip (cheiloschisis) and palate
which can be meet in 15-25% of cases
[1,2] They are caused a number of difficulties in presurgical preparation period of patients.
In
order to prevent the development of secondary deformities of maxillofacial part
the specialists [3,4] recommend to use an early presurgical correction of fragments
location of the upper jaw. It is reputed that early orthodontic treatment of
these children allows to normalize the process of feeding and to prevent
secondary deformities, progressing in the growth process, to eliminate that in
the future requires a long multistage complex treatment.
To treat such type of the
children in presurgical period
specialists more often use removable orthodontic appliances. In these cases,
treatment is characterized by long periods and it depends on many factors: the
magnitude of diastase, the timing of treatment beginning, the child habituation
to the apparatus and etc. The lack of these devices are: poor fixation in
edentulous jaws, the necessity for frequent doctor visits and the necessity for
repeated replacement of apparatuses. As a result, it leads to a considerable duration
of treatment, and it is not always possible to get the maximum convergence of
fragments of the upper jaw.
For the
present time more and more researchers and practitioners, orthodontists come to
the opinion about necessity to develop the new technologies during an early
stage of complex treatment of the children with congenital cleft lip and
palate. Particularly, the use of removable
orthotic devices with intraosseous fixation.
In 1990, in
press Latham R.A. and Millard have described a modified non-removable orthotic
device for repositioning of intermaxillary bone in children with bilateral
cleft lip and palate [5]. Recently it was found that the microimplants, in
addition to chewing can successfully carry the burden of the orthodontic
attachments components (springs, elastic and etc.), remaining motionless, and
without loss of osseointegration [6]. These data allowed us to expand the
indications for implantation and in the using of orthodontic technology during
the treatment of children with cleft lip and palate beginning from an early
age.
The purpose of the study is an explanation of presurgical
orthodontic training of the children with congenital cleft lip and palate by
using of microimplants.
Material and methods. In Almaty center of children
rehabilitation of congenital and hereditary pathology of maxillofacial 23
children with bilateral cleft lip and palate were under our observation. And
these children were prepared for surgery orthodontic treatment by using
microimplants. There was two compared groups of patients with congenital bilateral
cleft lip and palate with 25 patients in each: the first – operated patients
without presurgical orthodontic preparation, the second - operated patients after
presurgical orthodontic training by
removable orthodontic appliances.
The study of diagnostic models. The diagnostic model of all 73 patients was studied by
conventional methods in our modification. We proposed the modification which will
minimize errors, facilitate the measurement process and ultimately it has a
positive effect on the choice of method of used early orthopedic treatment. The
method includes: making a stone cast by the model of the upper jaw of the child
with congenital bilateral cleft lip and palate. The alveolar and palate
processes borders, an intermaxillary
bone and vomer borders have been marked by marker on stone cast and reference points are fixed. The model was photographed
by digital camera with a rigid fixation in the standard position. The received pictures were loaded in the
computer, where the graphic form of the alveolar
processes, palatal processes, intermaxillary bone and the vomer have been received
by AUTOCAD program where were marked reference points and the linear and
angular measurements have been produced. In the graphical representation the
area of splited fragments, the length of alveolar processess, width of cleft
palate along the whole length, the longitudinal dimensions of crevices, the
position of the fragments of the upper jaw by sagittal were studied. The
results were recorded in a specially designed patient`s card.
As a result of studies there were
observed different degree of
deformation of the side fragments of the alveolar process of the upper jaw,
protrusion of an intermaxillary bone,
the angle of deviation of the midline. Depending on the severity of the deformation
of the intermaxillary bone, we have identified three groups of the children
with mild case, moderate case, and severe case of bones deformity.
Computerized axial tomography was used during pronounced
deformation of the upper jaw to plan the location of fixing elements of supramaxillary
device. Computerized axial tomography study was made on the
X-ray computer tomograph Somatom-CR (Siemens) according to the bone
reconstruction program with high resolution (intersection gap is 2 mm, section
thickness is 2 mm, the voltage is 120kV, current strength is 22 gPa).The study
was made in a horizontal position of patient on his back. For fixation of an examined
child`s head the following were used: standard stand support behind his head and fixtures in the form of
special pads and fixing tapes.
The studies of the upper jaw were executed in axial and coronal projections with
reconstruction of images in the sagittal plane.On the obtained sections
anatomical formations of the upper jaw, the rudiments of teeth, vomer were
determined optimally.
The Surgical implant placement protocol for the creation of
support of supramaxillary non-removable devices with intraosseous fixation did
not differ from the standard methods of dental implantation. However, in the
hard palate area the surgery was planned carefully and executed with great
care. It was conditioned by the potential possibility of perforation of the
nasal cavity wall and other anatomical structures. Therefore, installed
implants in the hard palate were provided for short length (4-6 mm), which
depended on the volume of available bone. As the support elements and fixing
elements of non-removable orthopaedic devices with intraosseous
fixation, we used the microimplants (Absoanchor, Dentos corporation, Dagu,
Korea), designed specifically for use in orthodontics.
The depth of an implant immersion into the bone depended on the
method of further fixing to it the wire. If it is directly fixed with hinges
and screws, for convenience, the neck of the implant was placed at 1-2 mm above
the surface of the bone. In the case of used a special suprastructure to fix the wire, then the
implant is completely immersed in the formed bone bed.
Statistical methods. The research results were subjected to statistical analysis by
using of parametric and nonparametric statistical methods.
The results and discussion. The clinical and
biometric studies of children with congenital bilateral cleft lip and palate
during presurgical period revealed three
level of intermaxillary bone
deformation and the side fragments of
the upper jaw.
In the first
group of patients in the two cases, the maxillary bone was in the right
position, and in 22 patients, the transverse size of the intermaxillary bone
was 15 mm, protrusion – up to 7 mm, the angle of deviation from the median line
– from 0 up to 5 degrees, the displacement by the vertical plane was up to 2
mm. The distance between the front edges of the side fragments of the alveolar
process of the upper jaw is up to10 mm. The width of the defect on the border
of hard and soft palate was 14,8 ± 1,0 mm (Fig. 1a, b).


à) plaster
cast b)
schematic mo
Fig. 1 – The general view of plaster cast (à) and its` schematic
image (b)
in patient who was delivered
to the hospital (1level)
The second
level of an intermaxillary bone and the
side fragments of the upper jaw were found in 26 patients. They had a
transverse dimension of the intermaxillary bone -20 mm, protrusion - from 8 mm
up to 15 mm, the angle of deviation from the median line - up to 10 degrees, displacement from the vertical plane - from 2 up
to 4 mm. Distance between the front edges of the side fragments of the alveolar
process of the upper jaw was up to 15 mm. The width of the defect on the border
of hard and soft palate was 19,3 ± 1,0 mm (Fig. 2a, b).


à) plaster cast
b) schematic model image
Fig. 2 – The general view of
plaster cast (à) and its` schematic image (b)
in patient who was delivered to the hospital (2 level).
The third level of an
intermaxillary bone deformation and the side fragments of the upper jaw
were found in 23 patients. They had a transverse dimension of the
intermaxillary bone up to 25 mm, protrusion -from 16 mm and more, the angle of
deviation from the middle line - from 11 degrees and more, the displacement by
the vertical plane –from 5 mm and more. The distance between the front edges of
the side fragments of the alveolar process of the upper jaw was up to 25 mm.
The width of the defect on the border of hard and soft palate was 22,7 ± 1,0 mm
(fig. 3a, b).


à) plaster cast b) schematic model image
Fig.3 – The general view of plaster cast (à) and its` schematic
image (b)
in patient who was
delivered to the hospital (3 level).
The division of patients
with congenital bilateral cleft lip and palate into 3 groups before the treatment
had a practical importance, which was taken into account when planning the
treatment. Usually, we took to the treatment patients with the first and partially
with second part of deformation degree of Intermaxillary Bone, by using of removable orthodontic appliances
[7]. In the case of the intermaxillary
bones deformations of the third degree the presurgical preparation of patients
was performed by using of innovative technologies (non-removable devices, fixed
microimplants, or use of microimplants).
Clinical
application of microimplants. All patients (23 children) with congenital bilateral
cleft lip and palate with third degree of
intermaxillary bone deformation
the presurgical orthodontic treatment was executed by using of
microimplants. At the begining, the microimplants have been used in 6 patients
for intraosseous fixation of
supramaxillary non-removable orthodontic appliances (Fig. 4). Others 17 children
with such pathology used the microimplants as supporting elements of
orthodontic appliances (Fig.5).
Presurgical orthodontic preparation of patients was
carried out in several stages. At the beginning the plaster casts of the upper jaw have been taken from children at
the children dental clinic. After that,
the models of jaws were under
preparation. Analyzing the results data
of diagnostic models of the upper jaw and the parameters of the
computer-tomographic study the place of installation microimplants was
determined.
Within
children's clinic conditions of maxillo-facial surgery under the general
anesthesia, 6 patients have been installed by supramaxillary non-removable
devices that are fixed to the bone by using of microimplants (Figure). For this
purpose the holes in the projection angle of 45 °C to the top of the comb of
the alveolar process were prepared beforehand on the fixed fragments (two side
and maxillary bones). At the same time the both sides fragments were connected
by a V-shaped orthodontic screw for expansion of the side fragments of the
upper jaw. This structure of the apparatus used for the expansion of the side
fragments of the upper jaw and for repositioning the intermaxillary bone in the
correct position, forming the alveolar arch.

4 5
Fig. 4 -patient À-v Ñ. , 4 months., bilateral cleft lip and palate after fixation supramaxillary non-removable device to the upper
jaw fragments and to the intermandibular bone by
microimplants.
Fig. 5 -
patient V-yev, 5 months., bilateral
congenital cleft lip and palate after installation of the microimplants to the
upper jaw fragments and to the intermandibular bone
for orthodontic treatment.
The next step was to adapt the child to the
apparatus and the adjustment
of its
feeding, training the mother for hygiene care of oral cavity in child and
apparatus.The location of microimplants in the side fragments of the upper jaw
was monitored by panoramic radiographs. Depending on the children health
status the children were discharged
from the hospital on 6-7 days after surgery under the supervision of
orthodontist.
After the child's adaptation to the device
the screw is activated by 0.5 mm once in two days, with simultaneous activation
of an elastic traction on one link in the three days. Taking into account the
continued growth of divided alveolar process of upper jaw at length after
cheiloplasty the fragments cleft of the upper jaw shouldn`t be completely locked, leave the diastasis
between them on the width of the temporary tooth. The duration of an active
period ranged from 20 up to 30 days. One of the important step is the retentional
period, which ranged from 15 up to 30 days. After the end of retentional period
the device was removed, and primary cheiloplasty on both sides has been
conducted immediately.
Last time we use microimplants
in order to transfer separate fragments of the upper jaw and shape them into dental arch in account with severity degree of an
intermaxillary bone and side fragments of the alveolar processes of the upper
jaw. Such early orthodontic treatment is one of the few samples of an innovative
technology using during presurgical treatment of the children with
congenital bilateral cleft lip and palate before surgical intervention.
If the microimplants were used without using of supramaxillary orthodontic
apparatus the moving of the jaw fragments and the normalization of dentoalveolar arch have been occured during 1 month after the
start of orthodontic treatment.
Thus, the
deformations study of the alveolar and palatal processes of the intermaxillary bone and
palate in children with congenital bilateral cleft lip and palate has allowed
us to approach differentially to the various methods of presurgical preparation
of children with such pathology. The literature data and our own research are allowed
to emphasize if more time passes before the surgery without the orthopedic and
orthodontic treatment, then the deformation of the intermaxillary bone and vomer will be exacerbated. It is occurs because of the influence of tongue and nipple, which is
especially noticeable with very severe
deformation of the intermaxillary bone and vomer. So which means that in
children with congenital bilateral cleft lip and palate the deformity of the intermaxillary
bone is increased by age, and it`s depends on the initial indexes of the disease
severity (mild, mean, severe), and also depends on the ways of children
preparation for the surgery in the presurgical period.
The application of the microimplants within presurgical preparation of the patients with cleft lip (cheiloschisis) and cleft of palate plays the main role in
the surgical rehabilitation and it helps to the surgeons to make primary
surgery without any difficulties and also it has a positive effect on the
healing of lips tissues.
For comparison characteristic
of the results of the different methods of presurgilal preparation of the children with congenital cleft lip
and palate the anthropometric studies of the
jaws were done. (Table).
Table
- Anthropometric data received from the jaws models of the children with bilateral congenital cleft lip and palate,
prepared for the surgery by different methods.
|
Age periods |
Distribution
of the children by treatment methods |
||||||||
|
Without
presurgical orthodontic preparation (p=45) |
Treated
patients by T.V. Sharova`s method (p=48) |
The
patients treated by using of microimplants
(p=28) |
|||||||
|
Side of
displacement of the intermaxillary bone |
On the side from the intermaxillary bone displacement |
Total |
On the
side of the intermaxillary bone displacement |
On the side
from the intermaxillary
bone displacement |
Total |
On the
side of the intermaxillary bone displacement |
On the
side from the intermaxillary
bone displacement |
Total |
|
|
1 month |
8,5 ±0,52 |
10,9 ±0,42 |
19,4 ±0,47 |
10,5 ±0,83 |
11,5 ±0,65 |
22,0 ±0,74 |
8,4 ±0,92 |
11,6 ±0,87 |
20,0 ±0,71 |
|
3 months |
9,4 ±0,95 |
12,1 ±0,62 |
21,5 ±0,81* |
8,8 ±0,70 |
10,9 ±0,88 |
19,7 ±0,79* |
8,3 ±0,93 |
11,5 ±0,86 |
20,3 ±0,89 |
|
6 months |
9,8 ±0,92 |
12,7 ±0,74 |
22,5 ±0,83* |
6,4 ±0,57 |
7,6 ±0,62 |
14,0 ±0,59* |
1,2 ±0,27 |
1,4 ±0,32 |
2,6 ±0,29* |
|
12 months |
8,1 ±0,84 |
10,7 ±0,88 |
18,8 ±0,86 |
3,5 ±0,39 |
5,5 ±0,24 |
9,0 ±0,31* |
0,9 ±0,17 |
1,1 ±0,18 |
1,0 ±0,18* |
* The differences statistically are significant in
comparison with indices, received from newborn of 1 month (Ð<0,05).
As shown in the table, in patients of the comparable group with the growth
of a child with congenital bilateral cleft lip and palate the defects between
the intermaxillary bones and side fragments of the upper jaw increase and reach
its maximum at 6 months. After cheiloplasty it was observed statistically unauthentic
decrease of the bone defect.
In patients who were prepared for surgery with removable orthodontic devices, the bone
defects statistically and significantly decrease from 22,0 ± 0,74 mm up to 9,0 ± 0,31 mm, but the full butt contact
between the intermaxillary bone
and side fragments of the upper jaw was not occurred.
After
executed presurgical preparation with using of non-removable supramaxillary devices fixed
by microimplants, and also by microimplants it was reached the full frontal
contact between the intermaxillary bone and fragments of the upper jaw, which
was confirmed by static treatment of the material (P ˂ 0,05).
For illustration we present the stages of complex
treatment of the S.Yu-va patient (Fig. 6), who came to the clinic at 3 months
of age. After third degree determination of the intermaxillary bone the presurgical
patient preparation was carried out by using of the innovative technologies
(non-removable supramaxillary orthodontic device, fixed by microimplants). Bilateral
cheiloplasty was made at the age of 6 months and sparing palatoplasty-at the
age of 1.5 years.


À Á


 Ã


Ä Å


Æ Ç

È
Fig. 6 - Patient S.Yu-va, 3 months.,
diagnosis: Congenital bilateral cleft lip and palate (3 degree of the intermaxillary bone deformation):
À) Patient`s appearance when
delivered to the hospital,
B)
Plaster cast of the frgaments of the upper jaw before treatment,
C)
The fitting of supramaxillary orthopaedic device on the plaster cast,
D) The fixation of supramaxillary orthopaedic device by microimplants to the jaw
fragments,
E) Intermaxillary bone status in patient at the age of 6 months,
F)
The patient state after bilateral cheiloplasty,
G) Palate tissues status in patient
at the age of 1,5 month before surgery,
I) Palate tissues status in patient
at the age of 1,5 month after palatoplasty,
J) Patient`s appearance S. Yu-va at
the age of 2 years.
Summary. The modern design of
devices allows to reduce presurgical
preparation, to enter into the design active elements, to normalize the location
of intermaxillary bone and the upper
jaw form, and without special difficulties to produce a primary surgery of cheiloplasty,
after that the palatoplasty, accelerate the timing of complex rehabilitation of
patients with such complicated pathology of maxillofacial area as bilateral congenital cleft lip and palate with good aesthetic results.
Literature.
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and others: New in the treatment of the cleft lip and . // Materials of IV congress
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and rehabilitation in dentistry». – Vitebsk, 2000. – P. 342–344.
2. E.S. Katasonova Substantiation of using new technologies at
early growth of holiatry of the children with congenital bilateral
cleft lip and palate: author's abstract
of candidate dissertation – Almaty,
2010. – P. 20.
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Turley P.K., Kean C., Schur J. et all.
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Republic conference.– Ì., 1996. – P. 20.
6.
Millard D.R. Improved primary surgical and dental treatment of clefts / D.R. Millard,
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