Ahmerov A. A.

Bashkir state medical University (Ufa)

Autologous platelet plasma in the dental practice

 

Platelet-rich plasma is a preparation that is obtained from the patient's venous blood, through centrifugation in specially designed tubes. This autologous drug contains 6-7 times more platelets than the usual blood of the patient [2].

Efficiency, safety and minimally invasive - the basic requirements for modern technologies in medicine. These qualities satisfy the technology of application of autologous platelet plasma (TAP) is a method Plasmolifting, outdoor Russian scientists MD by Ahmerov R. R. and K. M. n Saradiel of the Russian Federation.  at the beginning of the XXI century. In addition to the method of dentistry has been successfully applied in dermatology and cosmetology, obstetrics and gynecology, orthopedics and traumatology, neurology, sports medicine.[3] Plasmoliftingtm method reduces the degree of inflammation, reduces the number of inflammatory cell infiltrates and inflammatory cells in the inflammatory focus, promotes the regeneration of gum tissue.[3]

For example, in the practice of a dentist-surgeon, the plasmolifting TAP method is used both when removing one tooth and when removing several teeth in different segments of the oral cavity, when removing teeth-"wisdom", when tooth - preserving operations, and most importantly, this method is very effective when closing perforations of the maxillary sinus. This technique allows to accelerate the healing process of the holes after tooth extraction or postoperative wounds, and reduce the risks of complications in the postoperative period, reduce pain and tissue edema [5].

Autologous platelet plasma can be used for conservative treatment of hypertrophic gingivitis in patients with fixed orthodontic appliances [7], as well as for the prevention of inflammatory complications in patients with pathology of periodontal patients on the background of orthodontic treatment [6, 9], in the treatment of periodontitis with pockets of destruction in the bone [8], for the treatment and prevention of periimplantitis in dental implant [1,4,5] .

Platelets contain growth factors that are highly active biological stimulants of regeneration processes. The use of autoplasma by this technology is simple, affordable, does not require complex equipment, safe and effective, it allows you to remove inflammation, reduce bleeding and reduce the duration of treatment [4]. The use of autoplasma for the treatment of chronic periodontitis can reduce the frequency of exacerbations, lengthen the remission of periodontal disease, promotes. In addition, plasma is autologous, which excludes infection and allergic reactions.[5]

For a more accurate idea of the action of the method Plasmolifting, and effectiveness of the injectable form of platelet autologous plasma in complex treatment and prophylaxis of gingivitis in patients undergoing orthodontic treatment with fixed appliances, monitored during 6 months of orthodontic 58 patients on supportive periodontal treatment. The study showed that in the group, where injections of platelet autologous plasma were carried out in order to prevent complications from periodontal tissues, the hygiene index was lower by 36.11% (p<0.01); the level of bleeding is 28.65% (p<0.01); the prevalence of inflammation in periodontal tissues is 24.97% lower than in the control group (p<0.01), which was a confirmation of the positive effect of the main group of procedures in patients and allows recommending the method for use in the complex of supporting periodontal therapy in this group of patients [9].

To date, the method (TAP) Plasmolifting has become widespread and recognized in practical dentistry due to the simplicity of preparation and use of the drug, its absolute safety, the absence of risks of rejection and the development of side effects.

List of references

1.       Аверьянов С.В., Гуляева О.А. Повышение эффективности консервативного лечения воспалительных осложнений после дентальной имплантации //Стоматология. 2017. Т. 96. № 6-2. С. 20.

2.                Ахмеров Р.Р., Овечкина М.В., Цыплаков Д.Э., Воробьев А.А., Т.Г. Мансурова. Технология Plasmolifting -инъекционная форма тромбоцитарной аутоплазмы для лечения хронических катаральных гингивитов//Пародонтология. -2012. -№4 (65). -C.80-84   

3.                Ахмеров Р. Р., Овечкина М. В., Цыплаков Д. Э., Воробьев А. А., Мансурова Т. Г. Технология Plasmolifting -инъекционная форма тромбоцитарной аутоплазмы для лечения хронических пародонтитов I-II степени тяжести//Пародонтология. 2013. №1 (66). С. 45.

4.       Гуляева О.А., Аверьянов С.В. Профилактика воспалительных осложнений после дентальной имплантации // Пародонтология.  2017.  № 2.  С. 84-88.

5.       Гуляева О.А., Аверьянов С.В., Солодкий В.Г. и др. Применение аутологичной тромбоцитарной плазмы в стоматологии //Учебное пособие. -Уфа.- 2016.- 75 с.

6.  Гуляева О.А. Способ лечения гипертрофического гингивита у пациентов с несъемной ортодонтической техникой с применением инъекционной формы аутологичной тромбоцитарной плазмы / патент на изобретение RUS 2626826 08.11.2016

7.  Гуляева О.А. Способ профилактики воспалительных заболеваний пародонта у пациентов с несъемной ортодонтической техникой с применением инъекционной формы аутологичной тромбоцитарной плазмы /
патент на изобретение RUS 2626825 08.11.2016

8.  Гуляева О.А., Буляков Р.Т. Способ лечения деструктивных форм хронического периодонтита с применением инъекционной формы аутологичной тромбоплазмы / патент на изобретение RUS 2627582 25.05.2016

9.  Гуляева О.А., Тухватуллина Д. Н., Солодкий В. Г. Применение тромбоцитарной аутологичной плазмы в комплексном лечении и профилактике гингивита у пациентов с несъемными ортодонтическими конструкциями //Пародонтология. 2016. №2 (79). С. 38-42.